SUPPORTS TARGETED COMFORT
(Menthol + Arnica + MSM)
SUPPORTS HEALTHY MICRO-CIRCULATION
(L-Arginine 7 g + Vitamin B6)
PROMOTES FAST LOCAL ABSORPTION
(Plant Oils + Lipid Carriers)
SOOTHES & CALMS PERIPHERAL TISSUE
(Aloe + Allantoin + Botanical Extracts)
Peripheral sensory discomfort is frequently associated with altered microvascular perfusion, inflammatory mediator signaling, and localized tissue stress. Clinicians supporting peripheral nerve discomfort commonly observe impaired nitric oxide signaling, oxidative imbalance, and reduced endothelial responsiveness at the local tissue level.
Nerve & Neuropathy Cream is a clinician-developed topical formulation designed for localized application to reinforce microvascular pathways, nitric oxide signaling, and tissue-calming mechanisms using clinically studied ingredients.
The formulation integrates nitric oxide precursors, topical counterirritants, antioxidant cofactors, and tissue-calming botanicals to support localized vascular and sensory physiology identified in controlled human research.
L-Arginine (7 g, 8.4%)supports nitric oxide production and endothelial responsiveness. Topical and systemic nitric oxide pathways have been studied in microvascular perfusion research.
Menthol (2,000 mg) activates TRPM8 receptors and has been evaluated in controlled studies for topical analgesic effects and cooling-mediated sensory modulation.
Arnica has been studied in controlled trials examining topical application and musculoskeletal discomfort endpoints.
MSM (Methylsulfonylmethane) has been evaluated in randomized controlled trials examining inflammatory and musculoskeletal parameters.
Vitamin B6 (Pyridoxine HCl) supports enzymatic processes involved in neurotransmitter synthesis and peripheral nerve metabolism.
Aloe Barbadensis Leaf Powder has been evaluated in dermatologic research for topical soothing and wound-support applications.
Tocopheryl Acetate (Vitamin E) supports lipid membrane stability and antioxidant balance in topical applications.
Apply to affected area up to 3–4 times daily.
For external use only.
Designed for localized use as part of a comprehensive peripheral support strategy.
Third-party laboratory tested
No artificial dyes or synthetic additives
Manufactured in the USA in GMP-compliant facilities
The ingredient components within this formulation have been evaluated in controlled human trials examining vascular, sensory, and inflammatory-related endpoints.
Evaluated in randomized trials assessing nitric oxide bioavailability and
endothelial-dependent vasodilation.
Böger RH. Circulation (1998)
https://pubmed.ncbi.nlm.nih.gov/9456007/
Studied in controlled trials examining topical cooling and sensory modulation
mechanisms.
Galeotti et al., Pain (2002)
https://pubmed.ncbi.nlm.nih.gov/12406524/
Evaluated in randomized controlled trials examining topical musculoskeletal discomfort
endpoints.
Widrig et al., Rheumatology International (2007)
https://pubmed.ncbi.nlm.nih.gov/17318618/
Examined in randomized trials evaluating inflammatory and joint-related parameters.
Kim et al., Osteoarthritis Cartilage (2006)
https://pubmed.ncbi.nlm.nih.gov/16309928/
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
